Little Known Facts About cees dekker.
Little Known Facts About cees dekker.
Blog Article
‘Sure, that is about proper. I try to find a physical comprehension of biological techniques in a very bottom-up way. I believe you could possibly distinguish three lines of exploration in my team in the mean time. The main concerns chromosome construction: How will you get a metre-extended DNA polymer folded and organised in this type of microscopic cell? We now have formulated visualisation techniques that enable us to review how, such as, SMC proteins loop DNA (video on Youtube) to be able to Make up chromosomes.
But how can morality, the dignity with the human being, my experience of your indicating of existence, adhere to within the movement of atoms? A purely naturalistic perspective fails below; a Christian viewpoint, I believe, is a way more fair technique to interpret these areas of fact.’
, Groningen scientists existing the effects in their efforts to produce labs far more sustainable and supply tricks for other labs.
Nanofabrication of electrodes with sub-5 nm spacing for transportation experiments on solitary molecules and metal clusters
2015, discovery that condensin is really a really versatile protein construction; and initial detection of DNA knots applying nanopores
The coiled-coil of your human Rad50 DNA mend protein includes specific segments of enhanced flexibility
Given that 2000 he moved to single-molecule biophysics and nanobiology, with investigate from DNA supercoiling scientific tests of nucleosomes and DNA mend proteins to DNA translocation by means of nanopores. Lately his investigate has centered on studying mobile division with microorganisms on chip, whilst his top fascination is within the direction of knowing synthetic cells.
Atomic drive microscopy displays that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative vogue
This "Cited by" depend includes citations to the following articles or blog posts in Scholar. Those marked * may very well be distinct through the short article during the profile.
Presently, we also understood that it ought to be attainable to work with only one semiconducting carbon nanotube for making a transistor — and we established out to make it. We stretched personal semiconducting nanotubes across metallic electrodes and used the fundamental silicon substrate for a gate electrode, developing The fundamental three-terminal structure of the discipline-result transistor (Fig.
Skip to key information Thank you for visiting mother nature.com. You happen to be utilizing a browser version with minimal assist for CSS. To obtain the most beneficial practical experience, we advise you use a far more up to date browser (or transform off compatibility method in Web Explorer).
Cees Dekker is Distinguished University Professor at TU Delft. Educated as being a physicist, he pioneered nanotechnology with several discoveries on carbon nanotubes inside the nineties. Considering that 2000, he moved to solitary-molecule biophysics and nanobiology. His existing analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, especially SMC motor protein; and (iii) developing a residing synthetic cell from lifeless molecules. Dekker is an elected member from the KNAW and fellow to the APS and the IOP.
2008, very first observation of protein-coated DNA translocation by means of nanopores; settled the origin in the electrophoretic force on DNA in nanopores; found a substantial velocity improve of microtubules in electric fields; discovered an anomalous electro-hydrodynamic orientation of microtubules; and fixed the origin of sounds in carbon nanotubes in liquid
Case in point (2) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in gray, the rim of the pore is highlighted in purple, along with a 3D rendering with the movement https://www.ceesdekker.net from the DNA rod is exhibited.